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DR RAMADHAN SULEIMAN MWAKUBAMBANYA

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Staff Information
PERSONAL DETAILS
Designation
LECTURER
Corporate Email
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Personal Email
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Job Category
Teaching
Division / Faculty
Faculty of Science
Directorate / Dept
DEPT. OF BIOCHEMISTRY & MOLECULAR BIO
Main Campus- Njoro
Address
P,O BOX 536-20115, EGERTON
ACADEMIC QUALIFICATIONS
  • 2009: PhD in Molecular Biology-Biomedicine, University of Crete (UoC), Greece
  • 2005: MSc. (Biochemistry) JKUAT, Kenya.
  • 2002: BSc. Biochemistry & Chemistry, JKUAT, Kenya.
  • 1996: KCSE, Kwale High School
  • 1993: KCPE, Mwakigwena Primary School
FIELDS OF SPECIALIZATION
  • Molecular Biology, Immunology and Molecular Parasitology
WORK EXPERIENCE

Teaching

  • 2009 to present: Lecturer, Biochemistry and Molecular Biology Department, Egerton University, Njoro, Kenya.
RESEARCH INTERESTS

Malaria research- understanding Parasite-mosquito interaction dynamics as a basis to develop malaria transmission blocking interventions, identification of plant medicinal compounds against Malaria, and other infectious diseases

LIST OF PUBLICATIONS

Intellectual Property-Patent 2021

  • Authors: Jackson Mbithi Muema, Joel Ltilitan Bargul, James Mutuku Mutunga, Meshack Amos Obonyo and Ramadhan Suleiman Mwakubambanya,.Title: Process of Blocking Transmission of Plasmodium Gametocytogenesis using Juliprosopine from Prosopis juliflora (Kenya Industrial Property Insitute). http://www.kipi.go.ke/images/docs/journals/January_2021_Journal.pdf

Peer Reviewed Scientific Publications 

  1. Muema JM, Mutunga JM, Obonyo MA, Getahun MN, Mwakubambanya RS, Akala HM, Cheruiyot AC, Yeda RA, Juma DW, Andagalu B, Johnson JL, Roth AL, Bargul JL. 2023. Isoliensinine from Cissampelos pariera rhizomes exhibits potential gametocytocidal and anti-malarial activities against Plasmodium falciparum clinical isolates. Malaria Journal. 22(1):161. https://doi: 10.1186/s12936-023-04590-7.
  2. Oseno B, Marura F, Ogwang R, Muturi M, Njunge J, Nkumama I, Mwakesi R, Mwai K, Rono MK, Mwakubambanya R, Osier F, Tuju J. 2022. Characterization of Anopheles gambiae D7 salivary proteins as markers of human-mosquito bite contact. Parasites Vectors. https://doi.org/1186/s13071-021-05130-5.
  3. Omondi BR., Muthui MK, Muasya WI, Orindi B, Mwakubambanya RS, Bousema T, Drakeley C, Marsh K, Bejon P and Kapulu MC. 2021. Antibody Responses to Crude Gametocyte Extract Predict Plasmodium falciparum Gametocyte Carriage in Kenya. Frontiers Immunology. https://doi.org/10.3389/fimmu.2020.609474
  4. Rono MK, Muturi CN, Ochieng R, Mwakubambanya R, Wachira FN, Mwangangi J, Njunge J, Mireji PO. 2019. Cadmium tolerance pathway in Anopheles gambiae senso stricto. Acta Trop. DOI: 1016/j.actatropica.2019.05.024
  5. Wanga LA, Wagara IN, Mwakubambanya R, Matasyoh JC. 2018. Antimicrobial activity of metabolites extracted from Zanthoxylum gilletii, Markhamia lutea and their endophytic fungi against common bean bacterial pathogens. African Journal of Biotechnology. 17(27), 870-879 https://academicjournals.org/journal/AJB/article-full-text-pdf/CBDC2B557691
  6. Khobondo J.O, Mwakubambanya, R, Wasike, C.B, and Kahi, A.K. 2017. Genetic and non-genetic sources of variation in natural antibodies titre values among indigenous chicken. American Journal of Research Communication, 5(7): 30-45. http://www.usa-journals.com/wp-content/uploads/2017/07/Khobondo_Vol57.pdf
  7. Khobondo J.O. Mwakubambanya R. Wasike, C.B. Kahi A.K. 2016. Variation and Repeatability of Natural Antibodies against Keyhole Limpet Hemocyanin of Indigenous Chicken of Kenya Genomics and Applied Biology, 7 (4) 1-8. http://hortherbpublisher.com/index.php/gab/article/html/2322/
  8. Njeru SN, Obonyo M, Nyambati S, Ngari S, Mwakubambanya R, Mavura H. 2016. Antimicrobial and cytotoxicity properties of the organic solvent fractions of Clerodendrum myricoides (Hochst.) R. Br. ex Vatke: Kenyan traditional medicinal plant. Journal of Intercultural Ethnopharmacology.  16; 5(3):226-32. https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4927126&blobtype=pdf
  9. Khobondo J O, Muasya T K, Miyumo S, Okeno T O, Wasike C B, Mwakubambanya R, Kingori A M and Kahi A K, 2015, Genetic and nutrition development of indigenous chicken in Africa (http://www.lrrd.org/lrrd27/7/khob27122.html)
  10. Tampaki Z, Mwakubambanya RS, Goulielmaki E, Kaforou S, Kim K, Waters AP, Carruthers VB, Siden-Kiamos I, Loukeris TG, Koussis K. 2015. Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium. PLoS ONE 10(3): e0121379 doi: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372514/pdf/pone.0121379.pdf
  11. Gachuhi S, Obonyo M, Odhiambo R, Swierczewski B and Mwakubambanya R. 2014, Differentiation of Entamoeba histolytica and Entamoeba dispar Complex by Multiplex Polymerase Chain Reaction, Scholars Academic Journal of Biosciences (SAJB), 2(11): 762-767. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1069.7877&rep=rep1&type=pdf
  12. Musasia FK, Isaac AO, Masiga DK, Omedo IA, Mwakubambanya R, Ochieng R, Mireji PO. 2013, Sex-specific induction of CYP6 cytochrome P450 genes in cadmium and lead tolerant Anopheles gambiae; Malaria Journal; 15; 12(1):97. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601984/pdf/1475-2875-12-97.pdf
  13. Graham SP, Pelle R, Yamage M, Mwangi DM, Honda Y, Mwakubambanya RS, de Villiers E.P, Abuya, E, Awino, E, Gachanja, J, Mbwika, F, Muthiani, AM, Muriuki, C, Nyanjui, JK, Onono, FO, Osaso J, Riitho V, Saya, RM, Ellis, SA, McKeever, DJ, MacHugh, ND, Gilbert, SC, Audonnet, J, Morrison I, van der Bruggen P and Taracha ELN. 2008, Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva, Infection and Immunity; 76(2):685-94. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223472/pdf/1244-07.pdf
POSTGRADUATE SUPERVISION
MASTERS LEVEL :

Completed

  1. Thesis: Validation of mosquito salivary gland antigens as serological markers of human exposure to Plasmodium falciparum infected Anopheles gambiae mosquitoes in Kilifi county, Kenya (Defended successfully 2022)
  2. Thesis: Characterization of sexual induction, vaccine candidate antigen and immune responses in Plasmodium falciparum gametocytes (2021)
  3. Thesis: Use of Zanthoxylum gilletii and Markhamia lutea and their endophytes to control bacterial pathogens of common bean (2018)
  4. Thesis:Comparative Analysis of Matrix Metalloproteinases in Anopheles gambiae Vector and Plasmodium falciparum Parasite (2017)
  5. Thesis: Trends and Infection Dynamics of Plasmodium Parasites in Human Hosts and Malaria Vectors from Western Kenya (2013)
PhD. LEVEL :

Completed

  1. Thesis: Discovery and Mechanistic Characterization of Potential Plant-Derived Malaria Transmission-Blocking Agents. PhD in Biochemistry, Jomo Kenyatta University of Agriculture and technology (JKUAT) (2022)
  2. Thesis: Genetics of immunity of the different ecotypes of indigenous chicken of Kenya, Egerton University (2019)
OTHER SOCIETIES
  1. 2019 to date: Biochemistry & Biotechnology Professionals Society of Kenya (BBPSK
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