Stephen Karori Mbuthia

Stephen Karori Mbuthia, PhD

Lecturer

Faculty of Science,

Department of Biochemistry,

Egerton University

P. O. Box 536, 20115 Egerton, Kenya

Mobile: +254 –722 49 35 72+254 –722 49 35 72

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it , This e-mail address is being protected from spambots. You need JavaScript enabled to view it

EDUCATION

2010-2015

PhD in Biochemistry and Molecular Biology

Egerton University

2005-2007

MSc -Biochemistry and Molecular Biology

Egerton University

1998-2003

BSc- Biochemistry

Egerton University

FIELD OF SPECIALIZATION

Biochemistry, Phytochemistry

WORK EXPERIENCE

June 2013 to date

Lecturer- Department of Biochemistry and Molecular Biology

Oct 2009 - June 2013

Assistant Lecturer- Department of Biochemistry and Molecular Biology

2008-2009

Pesticide Analyst- PCPB

KEY RESEARCH PROJECTS

2012 - 2014

Evaluation of the Anti-microbial, Anti-mutagenic, and Anti-cancer Properties of Black Tea Products from Kenya-EU DIV R&E

2013-date

Development of High Value Tea Products and Validation of their Potential Health Benefits-NCST

RECENT SELECTED PUBLICATIONS

1. Karori S. M., Wachira F. N., and Koech K.R. (2014). In-vitro antimicrobial and synergistic properties of water soluble green and black tea extracts.African Journal of Microbiology Research, 8:1527-1534.

  1. Karori Mbuthia, Francis Wachira, Raphael Ngure, Paul Mireji and Sabina Wachira (2014). Antimutagenic effect of Kenyan Tea cultivars in a bacterial test system. The Pharma Innovation, 3(8): 94-100
  2. Karori S.M,Wachira F.N, Ngure R.M and Mireji P. O (2014). Polyphenolic composition and antioxidant activity of Kenyan Tea cultivars. Journal of Pharmacognosy and Phytochemistry, 3(4): 105-116

4. Koech K. R., Wachira F. N., Ngure R. M., Wanyoko J. K., Bii C. and Karori S. M, Kerio L.C.(2014). Antioxidant, Antimicrobial and Synergistic activities of Tea polyphenols. African Crop Science Journal,22: 837-846. (ISSN 1021-9730)

5. Koech K. R., Wachira F. N., Ngure R. M., Orina I. A., Wanyoko J. K., Bii C. and Karori S. M (2013). Antimicrobial, synergistic and antioxidant activity of tea products. In: Microbial pathogens and strategies for combating them: Science, Technology and Education.Formatex Research Center. Pp 971-981 (ISBN 2: 978-84-942134-0-3)

6. Koech K. R., Wachira F. N., Ngure R. M., Wanyoko J. K., Bii C. and Karori S. M. (2013). Antibacterial and synergistic activity of different tea crude extracts against antibiotic resistant S. Aureus, E. Coli and clinical isolates of S. Typhi.Science Journal of Microbiology ISSN:2276-626X DOI: 10.7237/sjmb/115

7. Koech K. R., Wachira F. N., Ngure R. M., Orina I. A., Wanyoko J. K., Bii C. and Karori S. M. (2013). Antifungal activity of crude tea extracts. African Journal of Agricultural Research, 8: 2086-2089

  1. Wachira F.N., Karori S.M., Kerio L.C. and Wanyoko J.K. (2012). Cultivar Type and Antioxidant Potency of Tea Product. In: Tea in Health and Disease prevention. Elsevier, DOI: 10.1016/B978-0-12-384937-3.00008-2. ISBN: 778-0-12-384937-3.pp 3-18.
  2. Wachira F.N., Kamunya S., Karori S.M., Chalo R. and Maritim T. (2012). The Tea Plants; Botanical and aspects. In: Tea in Health and Disease prevention. Elsevier, DOI: 10.1016/B978-0-12-384937-3.00008-2. ISBN: 778-0-12-384937-3.pp 91-102.
  3. Karori, S.M.; Wachira, F.N.; Ngure, R.M. and Wanyoko, J.K. (2011). Effects of Tea on the Pathology and Survival Rates of Trypanosomabruceibrucei Infected Mice. Journal of Protozoology Research, 21: 1-7
  4. J.M. Kagira, N.Maina, J. Njenga, S. M. Karanja, S. M. Karori, and J.M. Ngotho (2011). Prevalence and Types of Co-infections in Sleeping Sickness Patients in Kenya (2000/2009). Journal of Tropical Medicine Volume 2011, Article ID 248914, 6 pages doi:10.1155/2011/248914

12. S.M Karori, F.N Wachira, R.M Ngure, J.K Wanyoko and J.M Kagira (2010). Effects of tea on inflammation: An animal model study. Tea,31(1): 13-21.

13. Karori S.M, Wachira F.N., Wanyoko J.K. and Ngure R.M. (2010). Free radical scavenging activities of Kenyan Teas.Tea,31(2): 44-52.

14. Ngure R.M, Karori S.M, Wachira W.M, Wachira F.N. (2009). Endotoxin and Acute phase proteins in serum of Trypanosomabruceibrucei infected mice following oral polymyxin B treatment. Parasitology International, 58: 325-329.

15. Karori, S.M.; Wachira, F.N., Ngure, R.M and Bahati, O. (2009). Effects of Azadiractaindica (neem) on Trypanosomabruceirhodesiense infected mice. Eastern Journal of Medicine,14: 2-9.

16. Karori, S.M.; Wachira, F.N.; Ngure, R.M. Ngugi, J.N and Wanyoko, J.K. (2008). Different Types of Tea Products Attenuate Chronic Inflammation Induced in Trypanosomabruceibrucei Infected Mice. Parasitology International, 57: 325-333.

  1. Karori, S.M.; Wachira, F.N.; Ngure, R.M. and Wanyoko, J.K. (2007). Antioxidant Capacity of Different Types of Tea Products. African Journal of Biotechnology, Volume 6(18): 2287-2296.

Consultancy

Tea Board of Kenya (2011-2012)

Drafting of Curriculum for the Tea Industry in Kenya

RESEARCH INTERESTS

Phytochemicals